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Article

Target Discovery for Drug Development Using Mendelian Randomization.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2022

Evans Daniel S

Abstract excerpt

Making drug development more efficient by identifying promising drug targets can contribute to resource savings. Identifying promising drug targets using human genetic approaches can remove barriers related to translation. In addition, genetic information can be used to identify potentially causal relationships between a drug target and disease. Mendelian randomization (MR) is a class of approaches used to...

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PMID: 36068458
DOI: 10.1007/978-1-0716-2573-6_1

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