Article

Deep transfer learning provides a <i>Pareto</i> improvement for multi-ancestral clinico-genomic prediction of diseases

2022-09-23

Abstract excerpt

Accurate genomic predisposition assessment is essential for the prevention and early detection of diseases. Polygenic scores and machine learning models have been developed for disease prediction based on genetic variants and other risk factors. However, over 80% of existing genomic data were acquired from individuals of European descent. As a result, clinico-genomic risk prediction is less accurate for non-Europe...

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Literature Corpus work: 158fb149-2ca8-5c90-8eee-6196e4bac3f0
DOI: 10.1101/2022.09.22.509055

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