Article

Improving Polygenic Risk Score Based Drug Response Prediction Using Transfer Learning

2025-03-13

Abstract excerpt

<title>Abstract</title> <p>Pharmacogenomics (PGx) studies aim to perform drug response prediction and patient stratification using genome-wide association study (GWAS) data from randomized clinical trials. Polygenic risk scores (PRS) are useful tools for PGx. By combining information across the genome, they have shown great promise in predicting disease risk and how patients respond to a particular treatment. A c...

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Literature Corpus work: e0c941c9-b64a-557d-87a4-789ddfffadbb
DOI: 10.21203/rs.3.rs-6173450/v1

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