Article
Gene Set Enrichment Analysis Detected Immune Cell-Related Pathways Associated with Primary Sclerosing Cholangitis.
BioMed research international - 1 Jan 2022
Luo Pan, Liu Lin, Hou Weikun, Xu Ke, Xu Peng
Abstract excerpt
Aim: To explore various immune cell-related causal pathways for primary sclerosing cholangitis (PSC). Methods: Immune cell-related pathway association study was conducted via integrative analysis of PSC GWAS summary and five immune cell-related eQTL datasets. The GWAS summary data of PSC was driven from 4,796 PSC cases and 19,955 healthy controls. The eQTL datasets of CD4+ T cells, CD8+ T cells, B cells, natural...
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