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Article

The skeletal muscle circadian clock regulates titin splicing through RBM20

1 Sept 2022

Abstract excerpt

Circadian rhythms are maintained by a cell-autonomous, transcriptional–translational feedback loop known as the molecular clock. While previous research suggests a role of the molecular clock in regulating skeletal muscle structure and function, no mechanisms have connected the molecular clock to sarcomere filaments. Utilizing inducible, skeletal muscle specific, Bmal1 knockout (iMS Bmal1 -/- ) mice, we showed...

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PMID: 36047761
DOI: 10.7554/elife.76478

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

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