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Skeletal muscle gene expression dysregulation in long-term spaceflights and aging is clock-dependent

3 Apr 2023

Abstract excerpt

The circadian clock regulates cellular and molecular processes in mammals across all tissues including skeletal muscle, one of the largest organs in the human body. Dysregulated circadian rhythms are characteristic of aging and crewed spaceflight, associated with, for example, musculoskeletal atrophy. Molecular insights into spaceflight-related alterations of circadian regulation in skeletal muscle are still...

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Share to Genetics, Aging, and Longevity in Model Organisms
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PMID: 37012297
DOI: 10.1038/s41526-023-00273-4

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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