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Article

Pathophysiological defects and transcriptional profiling in the RBM20-/- rat model.

PloS one - 1 Jan 2013

Guo Wei, Pleitner Jonathan M, Saupe Kurt W, Greaser Marion L

Abstract excerpt

Our recent study indicated that RNA binding motif 20 (Rbm20) alters splicing of titin and other genes. The current goals were to understand how the Rbm20(-/-) rat is related to physiological, structural, and molecular changes leading to heart failure. We quantitatively and qualitatively compared the expression of titin isoforms between Rbm20(-/-) and wild type rats by real time RT-PCR and SDS agarose...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24367651
DOI: 10.1371/journal.pone.0084281
PMCID: PMC3868568

Genes

RBM20
SDS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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Pathophysiological defects and transcriptional profiling in the RBM20-/- rat model.PMID 24367651Read ↗

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