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Article

mir152 hypomethylation as a mechanism for non-syndromic cleft lip and palate.

Epigenetics - 1 Dec 2022

Alvizi Lucas, Brito Luciano Abreu, Kobayashi Gerson Shigeru, Bischain Bárbara, da Silva Camila Bassi Fernandes, Ramos Sofia Ligia Guimaraes, Wang Jaqueline, Passos-Bueno Maria Rita

Abstract excerpt

Non-syndromic cleft lip with or without cleft palate (NSCLP), the most common human craniofacial malformation, is a complex disorder given its genetic heterogeneity and multifactorial component revealed by genetic, epidemiological, and epigenetic findings. Epigenetic variations associated with NSCLP have been identified; however, functional investigation has been limited. Here, we combined a reanalysis of NSCLP...

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Identifiers

PMID: 36047706
DOI: 10.1080/15592294.2022.2115606
PMCID: PMC9665146

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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