Article

Toward Understanding the Role of miRNAs in Cleft Palate Only: Observations from Patient Tissues and In Vitro Assays

2026-01-26

Abstract excerpt

Cleft palate only (CPO) is a multifactorial craniofacial malformation with significant genetic and epigenetic contributions. Among these, microRNAs (miRNAs) have emerged as key regulators of palate development, although their precise role in CPO pathogenesis remains incompletely elucidated. In this study, we performed a comprehensive miRNA expression analysis on palatal tissues from an Italian cohort of non-syndro...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 348235e8-902b-5a68-a9c0-3a8e1a20def7
DOI: 10.20944/preprints202601.1927.v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Toward Understanding the Role of miRNAs in Cleft Palate Only: Observations from Patient Tissues and In Vitro AssaysDOI 10.20944/preprints202601.1927.v1Read

Differential microRNA expression in cultured palatal fibroblasts from infants with cleft palate and controlsSemantic proximity Read

MicroRNAs in Palatogenesis and Cleft PalateSemantic proximity Read

MicroRNA-374a, -4680, and -133b suppress cell proliferation through the regulation of genes associated with human cleft palate in cultured human palate cellsSemantic proximity Read

A pilot study: Screening target miRNAs in tissue of nonsyndromic cleft lip with or without cleft palateSemantic proximity Read

MiRNA-149 as a Candidate for Facial Clefting and Neural Crest Cell Migration.Semantic proximity Read

Dexamethasone Suppresses Palatal Cell Proliferation through miR-130a-3pSemantic proximity Read

Advances in research regarding the roles of non-coding RNAs in non-syndromic cleft lip with or without cleft palate: A systematic review.Semantic proximity Read

MicroRNA and Rare Human Diseases.Semantic proximity Read

MicroRNA-655-3p and microRNA-497-5p inhibit cell proliferation in cultured human lip cells through the regulation of genes related to human cleft lipSemantic proximity Read

Assessment of differentially expressed plasma microRNAs in nonsyndromic cleft palate and nonsyndromic cleft lip with cleft palateSemantic proximity Read

MicroRNAs and Gene Regulatory Networks Related to Cleft Lip and PalateSemantic proximity Read

Genetic variants of microRNA processing genes and risk of non-syndromic orofacial clefts.Semantic proximity Read