Article
MiRNA-149 as a Candidate for Facial Clefting and Neural Crest Cell Migration.
Journal of dental research - 1 Mar 2022
Stüssel L G, Hollstein R, Laugsch M, Hochfeld L M, Welzenbach J, Schröder J, Thieme F, Ishorst N, Romero R Olmos, Weinhold L, Hess T, Gehlen J, Mostowska A, Heilmann-Heimbach S, Mangold E, Rada-Iglesias A, Knapp M, Schaaf C P, Ludwig K U
Abstract excerpt
Nonsyndromic cleft lip with or without palate (nsCL/P) ranks among the most common human birth defects and has a multifactorial etiology. Human neural crest cells (hNCC) make a substantial contribution to the formation of facial bone and cartilage and are a key cell type in terms of nsCL/P etiology. Based on increasing evidence for the role of noncoding regulatory mechanisms in nsCL/P, we investigated the role of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
