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Article

Genomic analysis of single nucleotide polymorphisms in malaria parasite drug targets.

Parasites & vectors - 30 Aug 2022

Gill Jasmita, Sharma Amit

Abstract excerpt

Malaria is a life-threatening parasitic disease caused by members of the genus Plasmodium. The development and spread of drug-resistant strains of Plasmodium parasites represent a major challenge to malaria control and elimination programmes. Evaluating genetic polymorphism in a drug target improves our understanding of drug resistance and facilitates drug design. Approximately 450 and 19 whole-genome assemblies...

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Identifiers

PMID: 36042490
DOI: 10.1186/s13071-022-05422-4
PMCID: PMC9425944

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