Impact on breast cancer susceptibility and clinicopathological traits of common genetic polymorphisms in <i>TP53</i>, <i>MDM2</i> and <i>ATM</i> genes in Sardinian women

Abstract excerpt

Common variants of genes involved in DNA damage correction [tumor protein p53 (<em>TP53</em>), murine double 2 homolog oncoprotein (<em>MDM2</em>) and ataxia‑telengiectasia mutated (<em>ATM</em>)] may serve a role in cancer predisposition. The purpose of the present study was to investigate the association of five variants in these genes with breast cancer risk and clinicopathological traits in a cohort of 261...

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