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Article

Mapping of promoter usage QTL using RNA-seq data reveals their contributions to complex traits.

PLoS computational biology - 1 Aug 2022

Kubota Naoto, Suyama Mikita

Abstract excerpt

Genomic variations are associated with gene expression levels, which are called expression quantitative trait loci (eQTL). Most eQTL may affect the total gene expression levels by regulating transcriptional activities of a specific promoter. However, the direct exploration of genomic loci associated with promoter activities using RNA-seq data has been challenging because eQTL analyses treat the total expression...

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Share to Genome-Wide Association Study
Share to Multifactorial Inheritance
Share to Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Promoter Regions, Genetic

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PMID: 36037215
DOI: 10.1371/journal.pcbi.1010436
PMCID: PMC9462676

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