Article
The mapping of a cDNA from the human X-linked Duchenne muscular dystrophy gene to the mouse X chromosome.
Nature - 1 Jan 2000
Brockdorff N, Cross G S, Cavanna J S, Fisher E M, Lyon M F, Davies K E, Brown S D
Abstract excerpt
The recent discovery of sequences at the site of the Duchenne muscular dystrophy (DMD) gene in humans has opened up the possibility of a detailed molecular analysis of the genes in humans and in related mammalian species. Until relatively recently, there was no obvious mouse model of this genetic disease for the development of therapeutic strategies. The identification of a mouse X-linked mutant showing muscular...
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