Localization of the region homologous to the Duchenne muscular dystrophy locus on the mouse X chromosome.

doi:10.1038/328168a0

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Article

Localization of the region homologous to the Duchenne muscular dystrophy locus on the mouse X chromosome.

Nature - 1 Jan 2000

Heilig R, Lemaire C, Mandel J L, Dandolo L, Amar L, Avner P

Abstract excerpt

Recent progress has resulted in part of the gene mutated in Duchenne and the milder Becker muscular dystrophies being cloned and has suggested that the gene itself extends over 1,000 to 2,000 kilobases (kb). To study how mutations in this gene affect muscle development and integrity, it would be...

Topics

Animals
Cell Line
Chromosome Mapping
Crosses, Genetic
Humans
Mice
Muscular Dystrophies
Muscular Dystrophy, Animal
Mutation
Nucleic Acid Hybridization
Sequence Homology, Nucleic Acid
X Chromosome

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