Close linkage of the murine locus bare patches to the X-linked visual pigment gene: implications for mapping human X-linked dominant chondrodysplasia punctata.

doi:10.1016/0888-7543(90)90162-n

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Article

Close linkage of the murine locus bare patches to the X-linked visual pigment gene: implications for mapping human X-linked dominant chondrodysplasia punctata.

Genomics - 1 Jul 1990

Herman G E, Walton S J

Abstract excerpt

The murine X-linked dominant mutation bare patches (Bpa) has a phenotype similar to and is likely homologous to human X-linked dominant chondrodysplasia punctata (CDPX2). Classic two-point linkage analysis in the mouse with distant markers suggested that Bpa maps near glucose-6-phosphate dehydrogenase (G6pd). We have confirmed the regional localization using interspecific matings with Mus spretus. We have also...

Topics

Animals
Chondrodysplasia Punctata
Chromosome Mapping
Crosses, Genetic
Deoxyribonucleases, Type II Site-Specific
Female
Genes
Genes, Dominant
Genetic Linkage
Glucosephosphate Dehydrogenase
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Mice

Muridae

Phenotype

Polymorphism, Restriction Fragment Length

Retinal Pigments

X Chromosome

Source

Open in PubMed

Identifiers

PMID: 1973136
DOI: 10.1016/0888-7543(90)90162-n

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1973136-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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