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Article

[The loss of CpG dinucleotides from DNA. I. Methylated and non-methylated genome compartments in eukaryotes with different levels of 5-methylcytosine in DNA].

Molekuliarnaia biologiia - 1 Jan 2000

Mazin A L, Vaniushin B F

Abstract excerpt

The methylation of cytosine residues in CpG significantly increases the frequency of m5CpG----TpG transitions in DNA and CpG dinucleotides are eliminated from the genome (CpG-suppression). In the millions of years of vertebrates evolution about 3 mol% of 5-methylcytosine have disappeared from the...

Topics

5-Methylcytosine
Animals
Base Composition
Cytidine Monophosphate
Cytosine
Cytosine Nucleotides
DNA
Dinucleoside Phosphates
Eukaryotic Cells
Genes
Guanosine
Methylation

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Mutation

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Identifiers

PMID: 3600627

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-3600627-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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