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Comprehensive Analysis of Fibroblast Activation Protein Expression in Interstitial Lung Diseases

19 Aug 2022

Abstract excerpt

Abstract Rationale Sustained activation of lung fibroblasts and the resulting oversynthesis of the extracellular matrix are detrimental events for patients with interstitial lung diseases (ILDs). Lung biopsy is a primary evaluation technique for the fibrotic status of ILDs, and is also a major risk factor for triggering acute deterioration. Fibroblast activation protein (FAP) is a long-known surface biomarker of...

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PMID: 35984444
DOI: 10.1164/rccm.202110-2414oc

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