Article
Cognitive performances across individuals at high genetic risk for schizophrenia, high genetic risk for bipolar disorder, and low genetic risks: a combined polygenic risk score approach.
Psychological medicine - 1 Jul 2023
Ohi Kazutaka, Nishizawa Daisuke, Sugiyama Shunsuke, Takai Kentaro, Fujikane Daisuke, Kuramitsu Ayumi, Hasegawa Junko, Soda Midori, Kitaichi Kiyoyuki, Hashimoto Ryota, Ikeda Kazutaka, Shioiri Toshiki
Abstract excerpt
BACKGROUND: Individuals with schizophrenia (SCZ) and bipolar disorder (BD) display cognitive impairments, but the impairments in those with SCZ are more prominent, supported by genetic overlap between SCZ and cognitive impairments. However, it remains unclear whether cognitive performances differ between individuals at high and low genetic risks for SCZ or BD. METHODS: Using the latest Psychiatric Genomics...
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