Article
The MMP-9 -1562 C/T polymorphism in the presence of metabolic syndrome increases the risk of clinical events in patients with coronary artery disease.
PloS one - 1 Jan 2014
Opstad Trine B, Arnesen Harald, Pettersen Alf Å, Seljeflot Ingebjørg
Abstract excerpt
BACKGROUND AND OBJECTIVES: Elevated levels of matrix metalloproteinase (MMP)-9 have been associated with the metabolic syndrome (MetS) and cardiovascular events. The MMP-9 -1562 C/T polymorphism has furthermore been shown as a risk factor for coronary artery disease (CAD). The non-favourable cardiometabolic state in MetS may increase the risk. We aimed to investigate the influence of MMP-9 -1562 C/T polymorphism...
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