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Improvements of nuclease and nickase gene modification techniques for the treatment of genetic diseases

26 Jul 2022

Abstract excerpt

Advancements in genome editing make possible to exploit the functions of enzymes for efficient DNA modifications with tremendous potential to treat human genetic diseases. Several nuclease genome editing strategies including Meganucleases (MNs), Zinc Finger Nucleases (ZFNs), Transcription Activator-like Effector Nucleases (TALENs) and Clustered Regularly Interspaced Short Palindromic Repeats-CRISPR associated...

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PMID: 35958050
DOI: 10.3389/fgeed.2022.892769

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