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Article

Arid5a Mediates an IL-17–Dependent Pathway That Drives Autoimmunity but Not Antifungal Host Defense

1 Sept 2022

Abstract excerpt

Abstract IL-17 contributes to the pathogenesis of certain autoimmune diseases, but conversely is essential for host defense against fungi. Ab-based biologic drugs that neutralize IL-17 are effective in autoimmunity but can be accompanied by adverse side effects. Candida albicans is a commensal fungus that is the primary causative agent of oropharyngeal and disseminated candidiasis. Defects in IL-17 signaling...

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Identifiers

PMID: 35940634
DOI: 10.4049/jimmunol.2200132

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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Arid5a Mediates an IL-17–Dependent Pathway That Drives Autoimmunity but Not Antifungal Host DefensePMID 35940634Read ↗

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