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Article

Focus on the tumor microenvironment: A seedbed for neuroendocrine prostate cancer

22 Jul 2022

Abstract excerpt

The tumor microenvironment (TME) is a microecology consisting of tumor and mesenchymal cells and extracellular matrices. The TME plays important regulatory roles in tumor proliferation, invasion, metastasis, and differentiation. Neuroendocrine differentiation (NED) is a mechanism by which castration resistance develops in advanced prostate cancer (PCa). NED is induced after androgen deprivation therapy and...

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PMID: 35938167
DOI: 10.3389/fcell.2022.955669

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