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Article

Osteoblast Lineage Cell-derived Sema3A Regulates Bone Homeostasis Independently of Androgens

5 Aug 2022

Abstract excerpt

Semaphorin 3A (Sema3A) coordinates bone resorption and formation under the control of estrogen signaling. However, the contribution of osteoblast lineage cell-derived Sema3A to vertebral homeostasis has remained unclear. Moreover, it is unknown whether androgen signaling is involved in Sema3A expression in osteoblast lineage cells. In this study, we show that osteoblast lineage cell-derived Sema3A plays a key...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 35931046
DOI: 10.1210/endocr/bqac126

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