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Article

Muscular myostatin gene expression and plasma concentrations are decreased in critically ill patients

3 Aug 2022

Abstract excerpt

BACKGROUND: The objective was to investigate the role of gene expression and plasma levels of the muscular protein myostatin in intensive care unit-acquired weakness (ICUAW). This was performed to evaluate a potential clinical and/or pathophysiological rationale of therapeutic myostatin inhibition. METHODS: A retrospective analysis from pooled data of two prospective studies to assess the dynamics of myostatin...

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PMID: 35922829
DOI: 10.1186/s13054-022-04101-1

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