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CSF1R defines the mononuclear phagocyte system lineage in human blood in health and COVID-19

1 Jan 2021

Abstract excerpt

Summary Mononuclear phagocytes defend tissues, present antigens, and mediate recovery and healing. To date, we lack a marker to unify mononuclear phagocytes in humans or that informs us about their origin. Here, we reassess mononuclear phagocyte ontogeny in human blood through the lineage receptor CSF1R, in the steady state and in COVID-19. We define CSF1R as the first sensitive and reproducible pan-phagocyte...

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PMID: 35915730
DOI: 10.1093/immadv/ltab003

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