Article
Age- and sex-specific associations between risk scores for schizophrenia and self-reported health in the general population.
Social psychiatry and psychiatric epidemiology - 1 Jan 2023
Paquin Vincent, Pries Lotta-Katrin, Ten Have Margreet, Bak Maarten, Gunther Nicole, de Graaf Ron, van Dorsselaer Saskia, Lin Bochao D, van Eijk Kristel R, Kenis Gunter, Richards Alexander, O'Donovan Michael C, Luykx Jurjen J, Rutten Bart P F, van Os Jim, Shah Jai L, Guloksuz Sinan
Abstract excerpt
PURPOSE: The health correlates of polygenic risk (PRS-SCZ) and exposome (ES-SCZ) scores for schizophrenia may vary depending on age and sex. We aimed to examine age- and sex-specific associations of PRS-SCZ and ES-SCZ with self-reported health in the general population. METHODS: Participants were from the population-based Netherlands Mental Health Survey and Incidence Study-2 (NEMESIS-2). Mental and physical...
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