Article
Interdependency of NINJ2 gene expression and polymorphism with susceptibility and response to interferon beta in patients with multiple sclerosis.
The International journal of neuroscience - 1 Apr 2024
Khorrami Mehdi, Saneipour Maryam, Moridnia Abbas, Shaygannejad Vahid, Sadeghi Erfan, Kassani Aziz, Sarmadi Akram, Mirmosayyeb Omid
Abstract excerpt
OBJECTIVE: Multiple sclerosis (MS) is a multifactorial inflammatory and autoimmune condition that lead to chronic neurodegeneration and central nervous system (CNS) demyelination that mainly affects young adults. The incidence and prevalence rate of MS considerably vary in ethnicities and geographic regions and affecting women more than men. Interferon-β (IFN-β) is the first-line disease management for MS, while...
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