Article
Genome-wide scan of 500,000 single-nucleotide polymorphisms among responders and nonresponders to interferon beta therapy in multiple sclerosis.
Archives of neurology - 1 Aug 2009
Comabella Manuel, Craig David W, Morcillo-Suárez Carlos, Río Jordi, Navarro Arcadi, Fernández Marta, Martin Roland, Montalban Xavier
Abstract excerpt
BACKGROUND: Interferon beta is 1 of 2 first-line treatments for relapsing-remitting multiple sclerosis (MS). However, not all patients respond to interferon beta therapy, and to date there is a lack of surrogate markers that reliably correlate with responsiveness to interferon beta therapy in MS....
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