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Article

Somatotropic Axis, Pace of Life and Aging

14 Jul 2022

Abstract excerpt

Mice with genetic growth hormone (GH) deficiency or GH resistance live much longer than their normal siblings maintained under identical conditions with unlimited access to food. Extended longevity of these mutants is associated with extension of their healthspan (period of life free of disability and disease) and with delayed and/or slower aging. Importantly, GH and GH-related traits have been linked to the...

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Identifiers

PMID: 35909509
DOI: 10.3389/fendo.2022.916139

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