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Human fibroblasts facilitate the generation of iPSCs-derived mammary-like organoids

28 Jul 2022

Abstract excerpt

BACKGROUND: Breast cancer is the most common malignancy in women worldwide, and its treatment largely depends on mastectomy. Patients after mastectomy suffer from crippled body image, self-esteem, and quality of life. Post-mastectomy breast reconstruction can improve patients' psychosocial health. Although silicone and fat have been widely used for breast reconstruction, they have remarkable limitations. Our...

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PMID: 35902878
DOI: 10.1186/s13287-022-03023-7

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