Article

Next-Generation Breast Organoids Capture Human Organogenesis with High-Resolution Live Imaging

2023-10-02

Abstract excerpt

Organoids have emerged as a powerful tool for modeling tissue growth and diseases. In this study, we introduce a groundbreaking organotypic culture technique that replicates the morphology, scale, and heterogeneity of human breast tissue, and includes a mesenchymal-like stromal component. A standout feature of this approach is the use of long-term live imaging at high temporal resolution to directly observe stem c...

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Literature Corpus work: df29699f-9ca8-5416-a9e2-9829c9761ea0
DOI: 10.1101/2023.10.02.560364

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