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Article

Androgen receptor mutations for precision medicine in prostate cancer.

Endocrine-related cancer - 1 Oct 2022

Shiota Masaki, Akamatsu Shusuke, Tsukahara Shigehiro, Nagakawa Shohei, Matsumoto Takashi, Eto Masatoshi

Abstract excerpt

Hormonal therapies including androgen deprivation therapy and androgen receptor (AR) pathway inhibitors such as abiraterone and enzalutamide have been widely used to treat advanced prostate cancer. However, treatment resistance emerges after hormonal manipulation in most prostate cancers, and it is attributable to a number of mechanisms, including AR amplification and overexpression, AR mutations, the expression...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 35900853
DOI: 10.1530/ERC-22-0140

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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