Article
Dissecting the roles of the androgen receptor in prostate cancer from molecular perspectives.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 May 2017
Hu Jieping, Wang Gongxian, Sun Ting
Abstract excerpt
Androgen receptor plays a pivotal role in prostate cancer progression, and androgen deprivation therapy to intercept androgen receptor signal pathway is an indispensable treatment for most advanced prostate cancer patients to delay cancer progression. However, the emerging of castration-resistant prostate cancer reminds us the alteration of androgen receptor, which includes androgen receptor mutation, the...
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