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Article

Androgen receptor plasticity and its implications for prostate cancer therapy.

Cancer treatment reviews - 1 Dec 2019

Snow Oliver, Lallous Nada, Singh Kriti, Lack Nathan, Rennie Paul, Cherkasov Artem

Abstract excerpt

Acquired resistance to a drug treatment is a common problem across many cancers including prostate cancer (PCa) - one of the major factors for male mortality. The androgen receptor (AR) continues to be the main therapeutic PCa target and despite the success of modern targeted therapies such as enzalutamide, resistance to these drugs eventually develops. The AR has found many ways to adapt to treatments including...

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Identifiers

PMID: 31698174
DOI: 10.1016/j.ctrv.2019.05.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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