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Genetic and Phenotypic Factors Affecting Glycemic Response to Metformin Therapy in Patients with Type 2 Diabetes Mellitus.

Genes - 23 Jul 2022

Nasykhova Yulia A, Barbitoff Yury A, Tonyan Ziravard N, Danilova Maria M, Nevzorov Ivan A, Komandresova Tatiana M, Mikhailova Anastasiia A, Vasilieva Tatiana V, Glavnova Olga B, Yarmolinskaya Maria I, Sluchanko Evgenia I, Glotov Andrey S

Abstract excerpt

Metformin is an oral hypoglycemic agent widely used in clinical practice for treatment of patients with type 2 diabetes mellitus (T2DM). The wide interindividual variability of response to metformin therapy was shown, and recently the impact of several genetic variants was reported. To assess the independent and combined effect of the genetic polymorphism on glycemic response to metformin, we performed an...

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Share to Blood Glucose
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Diabetes Treatment and Management

Share to Hypoglycemic Agents

Share to Metabolism, Diabetes, and Cancer

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Share to Pancreatic function and diabetes

Share to Polymorphism, Single Nucleotide

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Identifiers

PMID: 35893047
DOI: 10.3390/genes13081310
PMCID: PMC9330240

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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