The Effect of Genetic Variants of SLC22A2 (rs662301 and rs315978) on the response to Metformin in type 2 Saudi diabetic patients.

doi:10.1016/j.gene.2024.148648

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Article

The Effect of Genetic Variants of SLC22A2 (rs662301 and rs315978) on the response to Metformin in type 2 Saudi diabetic patients.

Gene - 15 Nov 2024

Alharbi Amani E, Ahmad Muhammad S, Damanhouri Zoheir A, Mosli Hala, Yaghmour Khaled A, Refai Fahd, Issa Noha M, Alkreathy Huda M

Abstract excerpt

PURPOSE: To investigate the allelic and genotypic frequencies of the two genetic variations, NC_000006.12: g.160275887C > T (rs662301) and NC_000006.12:g.160231826 T > C (rs315978), in the SLC22A2 gene among the Saudi population. The primary goal is to elucidate potential associations with these genetic variations and the response to metformin therapy over 6 months to enhance our knowledge of the genetic basis of...

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PMID: 38852696
DOI: 10.1016/j.gene.2024.148648

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