Insight into the drug resistance whole genome of Mycobacterium tuberculosis isolates from Khyber Pakhtunkhwa, Pakistan.

doi:10.1016/j.meegid.2021.104861

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Insight into the drug resistance whole genome of Mycobacterium tuberculosis isolates from Khyber Pakhtunkhwa, Pakistan.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Aug 2021

Khan Muhammad Tahir, Ali Sajid, Khan Anwar Sheed, Ali Arif, Khan Abbas, Kaushik Aman Chandra, Irfan Muhammad, Chinnasamy Sathishkumar, Zhang Shulin, Zhang Yu-Juan, Cui Zhilei, Wei Amie Jinghua, Wang Yanjie, Zhao Mingzhu, Liu Kejia, Wang Heng, Zeb Muhammad Tariq, Wei Dong Qing

Abstract excerpt

Whole genome sequencing (WGS) is one of the most reliable methods for detection of drug resistance, genetic diversity in other virulence factor and also evolutionary dynamics of Mycobacterium tuberculosis complex (MTBC). First-line anti-tuberculosis drugs are the major weapons against Mycobacterium tuberculosis (MTB). However, the emergence of drug resistance remained a major obstacle towards global tuberculosis...

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PMID: 33862292
DOI: 10.1016/j.meegid.2021.104861

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