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Novel Mutations in MPT64 Secretory Protein of Mycobacterium tuberculosis Complex.

International journal of environmental research and public health - 31 Jan 2023

Muhammad Noor, Khan Muhammad Tahir, Ali Sajid, Khan Taj Ali, Khan Anwar Sheed, Ullah Nadeem, Higazi Hassan, Ali Sara, Mohamed Salma, Qasim Muhammad

Abstract excerpt

Tuberculosis (TB) is a global health problem caused by the Mycobacterium tuberculosis complex (MTBC). These bacteria secrete various proteins involved in the pathogenesis and persistence of MTBC. Among the secretory proteins, MPT64 (Rv1980C) is highly conserved and is also known as a major culture filtrate that is used in rapid diagnosis of MTBC. In the current study, we aimed to find the mutation in this highly...

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PMID: 36767896
DOI: 10.3390/ijerph20032530
PMCID: PMC9915896

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