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Article

Motor-neuron-disease-like phenotype associated with IgLON5 disease.

Journal of neurology - 1 Nov 2022

Sista Sri Raghav, Crum Brian, Aboseif Albert, Devine Michelle F, Zekeridou Anastasia, Hammami M Bakri, Rezk Mohammed M, Truffert André, Lalive Patrice H, Kunchok Amy, McKeon Andrew, Dubey Divyanshu

Abstract excerpt

A growing spectrum of neurological manifestations are being recognized in association with IgLON5 autoimmunity, including recent reports of motor-neuron-disease-like phenotype. Here we describe four cases of IgLON5 autoimmunity with motor neuron involvement and evaluate an additional 109 probable or definite amyotrophic lateral sclerosis cases seen in our neuromuscular clinic for IgLON5-IgG seropositivity. The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 35857139
DOI: 10.1007/s00415-022-11262-0
PMCID: PMC9578379

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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