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Article

Novel MSH6 mutation predicted metastasis in eyelid and periocular squamous cell carcinoma.

Journal of the European Academy of Dermatology and Venereology : JEADV - 1 Dec 2022

Luo Y, Rao Y, Gu X, Chai P, Yang Y, Lin J, Xu X, Jia R, Xu S

Abstract excerpt

BACKGROUND: Our previous research revealed the relative local aggressiveness of eyelid and periocular squamous cell carcinoma (EPSCC), but its distinct genetic characteristics involved remain unknown. OBJECTIVES: We conducted this study based on next-generation sequencing to identify the genetic distinctiveness of EPSCC and damaging mutations for possible aetiology and poor prognosis. METHODS: We performed...

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PMID: 35855666
DOI: 10.1111/jdv.18454

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