Article
Congenital abnormalities and acute leukemia among children with Down syndrome: a Children's Oncology Group study.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology - 1 Oct 2008
Linabery Amy M, Blair Cindy K, Gamis Alan S, Olshan Andrew F, Heerema Nyla A, Ross Julie A
Abstract excerpt
Children with Down syndrome, due to their heightened risk of leukemia and increased prevalence of congenital abnormalities, comprise a valuable population in which to study etiology. A Children's Oncology Group study investigated the causes of childhood leukemia in children with Down syndrome diagnosed at ages 0 to 19 years during the period 1997-2002. Telephone interviews were completed with mothers of 158 cases...
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