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Polygenic risk score for embryo selection-not ready for prime time.

Human reproduction (Oxford, England) - 30 Sept 2022

Polyakov Alex, Amor David J, Savulescu Julian, Gyngell Christopher, Georgiou Ektoras X, Ross Vanessa, Mizrachi Yossi, Rozen Genia

Abstract excerpt

Numerous chronic diseases have a substantial hereditary component. Recent advances in human genetics have allowed the extent of this to be quantified via genome-wide association studies, producing polygenic risk scores (PRS), which can then be applied to individuals to estimate their risk of developing a disease in question. This technology has recently been applied to embryo selection in the setting of IVF and...

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Share to Assisted Reproductive Technology and Twin Pregnancy
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

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Share to Prenatal Screening and Diagnostics

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Source

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Identifiers

PMID: 35852518
DOI: 10.1093/humrep/deac159
PMCID: PMC9527452

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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