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Article

Effect of obesity on molecular characteristics of invasive breast tumors: gene expression analysis in a large cohort of female patients

29 Apr 2016

Abstract excerpt

BACKGROUND: Obesity is a risk factor for breast cancer in postmenopausal women and is associated with decreased survival and less favorable clinical characteristics such as greater tumor burden, higher grade, and poor prognosis, regardless of menopausal status. Despite the negative impact of obesity on clinical outcome, molecular mechanisms through which excess adiposity influences breast cancer etiology are not...

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PMID: 27148454
DOI: 10.1186/s40608-016-0103-7

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