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Methylome-Wide Association Study of Central Adiposity Implicates Genes Involved in Immune and Endocrine Systems

1 Sept 2020

Abstract excerpt

Aim: We conducted a methylome-wide association study to examine associations between DNA methylation in whole blood and central adiposity and body fat distribution, measured as waist circumference, waist-to-hip ratio and waist-to-height ratio adjusted for body mass index, in 2684 African–American adults in the Atherosclerosis Risk in Communities study. Materials & methods: We validated significantly associated...

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PMID: 32901515
DOI: 10.2217/epi-2019-0276

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