Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Mucosal viral infection induces a regulatory T cell activation phenotype distinct from tissue residency in mouse and human tissues.

Mucosal immunology - 1 May 2022

Traxinger Brianna, Vick Sarah C, Woodward-Davis Amanda, Voillet Valentin, Erickson Jami R, Czartoski Julie, Teague Candice, Prlic Martin, Lund Jennifer M

Abstract excerpt

Regulatory T cells (Tregs) mediate immune homeostasis, yet also facilitate nuanced immune responses during infection, balancing pathogen control while limiting host inflammation. Recent studies have identified Treg populations in non-lymphoid tissues that are phenotypically distinct from Tregs in lymphoid tissues (LT), including performance of location-dependent roles. Mucosal tissues serve as critical barriers...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Mice
Share to Mucous Membrane

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to T-Lymphocytes, Regulatory

Share to Virus Diseases

Source

Open in PubMed Open full text

Identifiers

PMID: 35821289
DOI: 10.1038/s41385-022-00542-7
PMCID: PMC9391309

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Mucosal viral infection induces a regulatory T cell activation phenotype distinct from tissue residency in mouse and human tissues.PMID 35821289Read ↗

Cervicovaginal tissue residence imprints a distinct differentiation program upon memory CD8 T cellsSemantic proximity Read ↗

Tissue-resident regulatory T cells accumulate at human barrier lymphoid organs.Semantic proximity Read ↗

Tissue-resident memory T cells.Semantic proximity Read ↗

An effector phenotype of CD8+ T cells at the junction epithelium during clinical quiescence of herpes simplex virus 2 infection.Semantic proximity Read ↗

Tissue-resident memory T cells in tissue homeostasis, persistent infection, and cancer surveillance.Semantic proximity Read ↗

Functional Diversity of Memory CD8 T Cells is Spatiotemporally ImprintedSemantic proximity Read ↗

Tissue-Resident-Memory CD8+ T Cells Bridge Innate Immune Responses in Neighboring Epithelial Cells to Control Human Genital Herpes.Semantic proximity Read ↗

Human Tissue-Resident Memory T Cells Are Defined by Core Transcriptional and Functional Signatures in Lymphoid and Mucosal Sites.Semantic proximity Read ↗

Human Tregs at the materno-fetal interface show site-specific adaptation reminiscent of tumor TregsSemantic proximity Read ↗

Human placental villi immune cells help maintain homeostasis <i>in utero</i>Semantic proximity Read ↗

A sustained type I IFN-neutrophil-IL-18 axis drives pathology during mucosal viral infectionSemantic proximity Read ↗

A transmissible γδ intraepithelial lymphocyte hyperproliferative phenotype is associated with the intestinal microbiota and confers protection against acute infection.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.