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Article

An effector phenotype of CD8+ T cells at the junction epithelium during clinical quiescence of herpes simplex virus 2 infection.

Journal of virology - 1 Oct 2012

Peng Tao, Zhu Jia, Phasouk Khamsone, Koelle David M, Wald Anna, Corey Lawrence

Abstract excerpt

Herpes simplex virus 2 infection is characterized by cycles of viral quiescence and reactivation. CD8(+) T cells persist at the site of viral reactivation, at the genital dermal-epidermal junction contiguous to neuronal endings of sensory neurons, for several months after herpes lesion resolution. To evaluate whether these resident CD8(+) T cells frequently encounter HSV antigen even during times of asymptomatic...

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Source

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Identifiers

PMID: 22811543
DOI: 10.1128/JVI.01237-12
PMCID: PMC3457322

Genes

CCL5
CCR1
GZMB
LTA
PRF1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

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