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WDR62 variants contribute to congenital heart disease by inhibiting cardiomyocyte proliferation

1 Jul 2022

Abstract excerpt

BACKGROUND: Congenital heart disease (CHD) is the most common birth defect and has high heritability. Although some susceptibility genes have been identified, the genetic basis underlying the majority of CHD cases is still undefined. METHODS: A total of 1320 unrelated CHD patients were enrolled in our study. Exome-wide association analysis between 37 tetralogy of Fallot (TOF) patients and 208 Han Chinese controls...

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PMID: 35808830
DOI: 10.1002/ctm2.941

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