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Article

Mutations in WDR62, encoding a centrosome-associated protein, cause microcephaly with simplified gyri and abnormal cortical architecture.

Nature genetics - 1 Nov 2010

Yu Timothy W, Mochida Ganeshwaran H, Tischfield David J, Sgaier Sema K, Flores-Sarnat Laura, Sergi Consolato M, Topçu Meral, McDonald Marie T, Barry Brenda J, Felie Jillian M, Sunu Christine, Dobyns William B, Folkerth Rebecca D, Barkovich A James, Walsh Christopher A

Abstract excerpt

Genes associated with human microcephaly, a condition characterized by a small brain, include critical regulators of proliferation, cell fate and DNA repair. We describe a syndrome of congenital microcephaly and diverse defects in cerebral cortical architecture. Genome-wide linkage analysis in tw...

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Identifiers

PMID: 20890278
DOI: 10.1038/ng.683
PMCID: PMC2969850

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20890278-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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