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Article

Microcephaly-associated protein WDR62 regulates neurogenesis through JNK1 in the developing neocortex.

Cell reports - 16 Jan 2014

Xu Dan, Zhang Feng, Wang Yaqing, Sun Yiming, Xu Zhiheng

Abstract excerpt

Mutations of WD40-repeat protein 62 (WDR62) have been identified recently to cause human MCPH (autosomal-recessive primary microcephaly), a neurodevelopmental disorder characterized by decreased brain size. However, the underlying mechanism is unclear. Here, we investigate the function of WDR62 in brain development and the pathological role of WDR62 mutations. We find that WDR62 knockdown leads to premature...

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Identifiers

PMID: 24388750
DOI: 10.1016/j.celrep.2013.12.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Microcephaly-associated protein WDR62 regulates neurogenesis through JNK1 in the developing neocortex.PMID 24388750Read ↗

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